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These studies demonstrated significant weight loss and metabolic improvements with the standard weekly schedule

In fact, research has shown that women with overweight or obesity who participated in weight loss programs were more likely to become pregnant than those who did not undertake weight loss interventions

doi: 10.1016/S0021-9258(19)69015-0 3 LundPKGoodmanRHMontminyMRDeePCHabenerJF

But it's a fairly simple on/off nucleus and if you alter its modulation it's not sophisticated enough that you can say, I want this behavior to go away, but I want that one to be preserved. The person has to make more of a choice-driven, I'm going to do this because it's good for me and I'd like to continue this. Not that it may feel as good as it used to

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